Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MTOR | P42345 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | ADK | P55263 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073980 | 1.00 | LMNA (0.57) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL1737343 | 0.88 | LMNA (0.58) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL1737852 | 0.88 | LMNA (0.58) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL6729928 | 0.88 | LMNA (0.58) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL19849643 | 0.88 | LMNA (0.55) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL18503322 | 0.88 | LMNA (0.55) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL31231550 | 0.88 | LMNA (0.55) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL13885753 | 0.88 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14440910 | 0.87 | LMNA (0.57) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL25354000 | 0.86 | ADORA3 (0.56) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439604-A | 7-β-D-Arabinofuranosyl-7H-pyrrolo[2,3-d]pyrimidine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0057548-A2 | 7-Beta-D-arabinofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine 5'-phosphate compounds useful as antiviral agents, pharmaceutical compositions containing the compounds, and processes for producing the compounds | WARNER-LAMBERT COMPANY (US) | 1982-08-11 | — | — | EP | disclosed |