Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070855 | 0.83 | RAB9A (0.50) | RAB9AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11073721 | 0.81 | MAPT (0.46) | RAB9AMAPTCYP1A2IKBKBALDH1A1 | |
| SCHEMBL644698 | 0.73 | GAA (0.72) | RAB9AMAPTGAALMNASMN1; SMN2 | |
| SCHEMBL12922084 | 0.73 | KMT2A (0.54) | RAB9AMAPTGAACYP1A2RECQL | |
| SCHEMBL11074149 | 0.71 | PRNP (0.45) | RAB9AMAPTCYP1A2IKBKBALDH1A1 | |
| SCHEMBL9301000 | 0.70 | TDP1 (0.45) | MAPTGAACYP1A2RECQLALDH1A1 | |
| SCHEMBL27321802 | 0.70 | RAB9A (0.63) | RAB9AMAPTGAACYP1A2ALDH1A1 | |
| SCHEMBL16517127 | 0.69 | KDM4E (0.41) | MAPTGAACYP1A2RECQLIDO1 | |
| SCHEMBL14898128 | 0.69 | PLAU (0.59) | RAB9AMAPTSMN1; SMN2TSHRNPC1 | |
| SCHEMBL11634857 | 0.69 | DCUN1D1 (0.48) | RAB9AMAPTIKBKBALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112623-A2 | 3-Aryl-5-pyrazole-carboxylic-acid derivatives, their preparation and pharmaceutical compositions | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |