Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838889 | 0.87 | KDM4E (0.50) | KDM4EGAAKMT2ACES2CES1 | |
| SCHEMBL12837765 | 0.80 | KDM4E (0.42) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL14225090 | 0.80 | KDM4E (0.38) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL11998008 | 0.80 | RXRA (0.47) | KDM4EGAACA1CA2SMN1; SMN2 | |
| SCHEMBL177224 | 0.79 | CA1 (0.50) | KDM4EPARP1KMT2AALDH1A1CA1 | |
| SCHEMBL3087859 | 0.79 | PARP1 (0.56) | PARP1F2MAPTKMT2ACES2 | |
| SCHEMBL30197284 | 0.79 | CA1 (0.50) | KDM4EPARP1KMT2AALDH1A1CA1 | |
| SCHEMBL15855009 | 0.79 | CA12 (0.46) | KDM4EGAAMAPTALDH1A1CA1 | |
| SCHEMBL414382 | 0.78 | CA1 (0.52) | KDM4EGAAF2MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL3767130 | 0.78 | RXRA (0.49) | KDM4EPARP1KMT2AALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |