Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069627 | 0.96 | HTR1A (0.31) | HTR1AHTR1D | |
| SCHEMBL11075656 | 0.93 | HTR1A (0.31) | HTR1AHTR1D | |
| SCHEMBL11068797 | 0.89 | KCNN4 (0.32) | — | |
| SCHEMBL11076893 | 0.88 | — | — | |
| SCHEMBL11069257 | 0.87 | HTR1D (0.33) | HTR1AHTR1D | |
| SCHEMBL11076146 | 0.86 | HTR1D (0.36) | KCNH2HTR1AHTR1D | |
| SCHEMBL11065844 | 0.82 | OPRM1 (0.34) | KCNH2 | |
| SCHEMBL11067219 | 0.82 | HTR1D (0.38) | HTR1AHTR1D | |
| SCHEMBL11075316 | 0.81 | OPRM1 (0.31) | HTR1A | |
| SCHEMBL11076951 | 0.79 | HTR1A (0.31) | HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |