Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.78 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067365 | 0.91 | TBXAS1 (0.79) | TBXAS1CYP11B2FAAH | |
| SCHEMBL11010003 | 0.91 | TBXAS1 (0.79) | TBXAS1CYP11B2FAAH | |
| SCHEMBL3513494 | 0.88 | TBXAS1 (1.00) | TBXAS1CYP11B2ALDH1A1 | |
| SCHEMBL11009473 | 0.88 | TBXAS1 (1.00) | TBXAS1CYP11B2ALDH1A1 | |
| SCHEMBL11006075 | 0.88 | TBXAS1 (1.00) | TBXAS1CYP11B2ALDH1A1 | |
| SCHEMBL11009385 | 0.87 | TBXAS1 (0.85) | TBXAS1CYP11B2ALDH1A1 | |
| SCHEMBL11007597 | 0.86 | TBXAS1 (1.00) | TBXAS1CYP11B2ALDH1A1 | |
| SCHEMBL9237199 | 0.86 | TBXAS1 (0.58) | TBXAS1FAAHCTNNB1TNFMEN1 | |
| SCHEMBL11068897 | 0.85 | TBXAS1 (0.62) | TBXAS1CYP11B2CTNNB1MEN1KMT2A | |
| SCHEMBL11068112 | 0.85 | TBXAS1 (0.79) | TBXAS1CYP11B2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478842-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |