Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544033 | 0.87 | TBXAS1 (0.74) | TBXAS1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL11074372 | 0.86 | TBXAS1 (0.78) | TBXAS1CTNNB1TNFFAAHMEN1 | |
| SCHEMBL9282505 | 0.83 | TBXAS1 (0.51) | TBXAS1GAACTNNB1MEN1KMT2A | |
| SCHEMBL12938925 | 0.79 | TNF (0.64) | CTNNB1TNFCNR1CNR2KDM4E | |
| SCHEMBL1004476 | 0.78 | TNF (0.63) | CTNNB1TNFFAAHCNR1CNR2 | |
| SCHEMBL1004093 | 0.78 | TNF (0.63) | CTNNB1TNFFAAHCNR1CNR2 | |
| SCHEMBL10984266 | 0.78 | TBXAS1 (0.60) | TBXAS1CTNNB1TNFFAAHMEN1 | |
| SCHEMBL11067365 | 0.76 | TBXAS1 (0.79) | TBXAS1FAAH | |
| SCHEMBL11010003 | 0.76 | TBXAS1 (0.79) | TBXAS1FAAH | |
| SCHEMBL355499 | 0.75 | TNF (0.62) | CTNNB1TNFFAAHCNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643059-A1 | 3-(3-Pyridinyl)-1H-indoles as thromboxane A2 synthetase inhibitors | Pfizer Limited (GB) | 1995-03-15 | — | — | EP | disclosed |