Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL11264556 | 1.00 | LTA4H (0.73) | LTA4HTSHRMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL28176491 | 1.00 | LTA4H (0.73) | LTA4HTSHRMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL11183529 | 1.00 | LTA4H (0.73) | LTA4HTSHRMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL9334093 | 0.97 | LTA4H (0.76) | LTA4HTSHRMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL710065 | 0.89 | LTA4H (0.61) | LTA4HTSHRMMP2MMP3MMP9 | |
| Diphenylether SCHEMBL11637824 | 0.89 | LTA4H (0.61) | LTA4HTSHRALDH1A1KMT2A | |
| SCHEMBL28596484 | 0.88 | LTA4H (0.65) | LTA4HTSHRMMP2MMP3MMP9 | |
| SCHEMBL27639404 | 0.88 | LTA4H (0.96) | LTA4HTSHRMLNRNR1I2ESR1 | |
| Diphenylether SCHEMBL11580362 | 0.88 | LTA4H (0.59) | LTA4HESR1CHRM2ADRA2AADORA3 | |
| Diphenylether SCHEMBL27695376 | 0.88 | LTA4H (0.59) | LTA4HTSHRMMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043612-B1 | POLYGLYCIDYL ETHERS OF DIPHENYLOL ALKANES, PREPARATION AND USE IN CURABLE COMPOSITIONS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1984-07-25 | — | — | EP | disclosed |
| US-4345060-A | Diglycidyl ethers of diphenylol alkanes, their preparation and use in curable compositions | SHELL OIL COMPANY (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0043612-A1 | Polyglycidyl ethers of diphenylol alkanes, preparation and use in curable compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-01-13 | — | — | EP | disclosed |