Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979495 | 0.75 | ALDH1A1 (0.34) | NPC1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL11510149 | 0.71 | CYP1A2 (0.47) | ALDH1A1LMNASMN1; SMN2HPGDPOLB | |
| SCHEMBL9427777 | 0.70 | KMT2A (0.35) | NPC1ALDH1A1RAB9AHPGDPOLB | |
| SCHEMBL11321294 | 0.69 | CYP1A2 (0.34) | CYP1A2CYP2C8CYP2B6 | |
| SCHEMBL850907 | 0.69 | ALDH1A1 (0.38) | NPC1ALDH1A1LMNARAB9AHPGD | |
| SCHEMBL11786403 | 0.68 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2POLBTDP1 | |
| SCHEMBL11322059 | 0.67 | MAOA (0.38) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C8 | |
| SCHEMBL11509947 | 0.67 | CYP1A2 (0.41) | LMNACYP1A2CYP2C8CYP2B6 | |
| SCHEMBL11510161 | 0.66 | ALDH1A1 (0.42) | NPC1ALDH1A1LMNASMN1; SMN2RAB9A | |
| SCHEMBL949551 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452630-A | Stable, heat-resistant solutions of pesticidal carbamates | MONTEDISON S.P.A. (IT) | 1984-06-05 | — | — | US | disclosed |