SCHEMBL11075359

SCHEMBL11075359

COC(=O)Oc1cc2ccccc2oc1=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.60
ALDH1A1 P00352 5/20 0.60
HPGD P15428 4/20 0.60
ATM Q13315 1/20 0.56
MAOA P21397 3/20 0.56
CYP1A2 P05177 3/20 0.56
HSD17B10 Q99714 2/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
LMNA P02545 1/20 0.56
MAOB P27338 9/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
CA12 O43570 2/20 0.53
CA9 Q16790 2/20 0.53
NT5E P21589 1/20 0.53
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
MAPT P10636 3/20 0.52
NPC1 O15118 1/20 0.52
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045399 0.86 KDM4E (0.61) KDM4EALDH1A1HPGDATMMAOA
Methyl Alcohol SCHEMBL27953712 0.84 KDM4E (0.59) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL8304474 0.84 MAOB (0.59) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL7537579 0.84 POLB (0.54) KDM4EALDH1A1HPGDATMMAOA
Bicarbonate SCHEMBL4227922 0.83 KDM4E (0.58) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL6036799 0.83 MAOB (0.58) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL4466591 0.82 MAOB (0.50) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL11081635 0.81 HPGD (0.53) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL5057152 0.81 MAOB (0.52) KDM4EALDH1A1HPGDATMMAOA
SCHEMBL28749574 0.81 MAOB (0.59) KDM4EALDH1A1HPGDATMMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030703-B1 PROCESS FOR THE PREPARATION OF COUMARIN COMPOUNDS BASF Aktiengesellschaft (DE) 1984-03-21 EP disclosed
EP-0030703-A1 Process for the preparation of coumarin compounds BASF Aktiengesellschaft (DE) 1981-06-24 EP disclosed