Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045399 | 0.82 | KDM4E (0.61) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL11075359 | 0.81 | KDM4E (0.60) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL1116527 | 0.81 | FLT3 (0.47) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| Methyl Alcohol SCHEMBL27953712 | 0.81 | KDM4E (0.59) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL7537579 | 0.80 | POLB (0.54) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| Bicarbonate SCHEMBL4227922 | 0.80 | KDM4E (0.58) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL6036799 | 0.79 | MAOB (0.58) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL11081635 | 0.78 | HPGD (0.53) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL8304474 | 0.78 | MAOB (0.59) | MAOBKDM4EALDH1A1CYP1A2MAOA | |
| SCHEMBL9956827 | 0.76 | KDM4E (0.56) | MAOBKDM4EALDH1A1CYP1A2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216804-B2 | pairs of orthogonal-tRNAs (O-tRNAs) and orthogonal aminoacyl-tRNA synthetases (O RSs) that do not interact with the host cell translation machinery | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-07-10 | — | — | US | disclosed |
| US-20080233611-A1 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233611-A1 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids | AARS1, NSUN3, OSGEP | MAOB 3715/4885KDM4E 2536/4885ALDH1A1 4157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.