Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3140885 | 0.87 | MAPT (0.54) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL9609255 | 0.84 | LMNA (0.33) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL1134609 | 0.83 | MAPT (0.58) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL9609163 | 0.82 | MAPT (0.52) | MAPTLMNAKDM4EDUSP3MEN1 | |
| SCHEMBL27865301 | 0.81 | EGLN1 (0.45) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL846984 | 0.81 | EGLN1 (0.45) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL18585598 | 0.80 | LMNA (0.40) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL13331312 | 0.79 | LMNA (0.43) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL28875656 | 0.78 | EGLN1 (0.42) | MAPTEGLN1KDM6BKDM5CPHF8 | |
| SCHEMBL18585442 | 0.77 | PDE4A (0.39) | EGLN1KDM6BKDM5CPHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481353-A | SURGICAL SUTURES | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |