Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075462 | 0.84 | MAPT (0.42) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL3140885 | 0.73 | MAPT (0.54) | LMNAMAPT | |
| SCHEMBL1134609 | 0.70 | MAPT (0.58) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL13403058 | 0.69 | — | — | |
| SCHEMBL9609163 | 0.69 | MAPT (0.52) | LMNAMAPT | |
| SCHEMBL846984 | 0.69 | EGLN1 (0.45) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL27865301 | 0.69 | EGLN1 (0.45) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL18585598 | 0.68 | LMNA (0.40) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL13331312 | 0.66 | LMNA (0.43) | LMNAMAPTKDM6BKDM5CEGLN1 | |
| SCHEMBL28875656 | 0.66 | EGLN1 (0.42) | LMNAMAPTKDM6BKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2457921-A2 | AUREOLIC ACID DERIVATIVES, THE METHOD FOR PREPARATION THEREOF AND THE USES THEREOF | EntreChem, S.L. (ES) | 2012-05-30 | — | — | EP | disclosed |