Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31310155 | 0.91 | LMNA (0.55) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL10878634 | 0.89 | LMNA (0.58) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL10975174 | 0.87 | LMNA (0.51) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL11011671 | 0.86 | PPARG (0.42) | MMP2MMP9SCN9A | |
| SCHEMBL11001989 | 0.85 | LMNA (0.48) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL11091004 | 0.83 | NPSR1 (0.43) | LMNARAB9ASCN9AMAPTNPSR1 | |
| SCHEMBL11090211 | 0.82 | LMNA (0.57) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL11012946 | 0.82 | FFAR1 (0.61) | LMNALIPERAB9ASCN9AMAPT | |
| SCHEMBL11010984 | 0.81 | LMNA (0.59) | LMNALIPERAB9AMMP2MMP9 | |
| SCHEMBL11010992 | 0.81 | LMNA (0.59) | LMNALIPERAB9AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469872-A | Substituted pyridyloxyphenoxyhydroxyketones | ZOECON CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |