Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009311 | 0.87 | ALDH1A1 (0.45) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11012707 | 0.85 | ALDH1A1 (0.59) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11011172 | 0.83 | ALDH1A1 (0.51) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11075585 | 0.83 | LMNA (0.55) | NPSR1LMNAMAPTSCN9AHTT | |
| SCHEMBL11304859 | 0.82 | LMNA (0.52) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL10946082 | 0.81 | LMNA (0.53) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10946104 | 0.81 | LMNA (0.51) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL10882340 | 0.80 | MAPT (0.50) | NPSR1LMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11011671 | 0.80 | PPARG (0.42) | SCN9AFPR2 | |
| SCHEMBL11089385 | 0.79 | ALDH1A1 (0.43) | NPSR1LMNATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469872-A | Substituted pyridyloxyphenoxyhydroxyketones | ZOECON CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |