Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078645 | 0.94 | SLC6A3 (0.36) | SLC6A3OPRL1OPRM1OPRK1PSEN1 | |
| SCHEMBL11071160 | 0.91 | SLC6A3 (0.38) | SLC6A3OPRL1OPRM1OPRK1PSEN1 | |
| SCHEMBL11069208 | 0.88 | OPRL1 (0.38) | OPRL1OPRM1ALDH1A1LMNAPTBP1 | |
| SCHEMBL11067453 | 0.87 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL11078182 | 0.86 | SLC6A3 (0.32) | SLC6A3OPRL1 | |
| SCHEMBL11074300 | 0.84 | SLC6A3 (0.32) | SLC6A3OPRL1OPRM1OPRK1 | |
| SCHEMBL11078360 | 0.84 | OPRL1 (0.37) | SLC6A3OPRL1OPRM1OPRK1PSEN1 | |
| SCHEMBL11066404 | 0.82 | OPRL1 (0.39) | SLC6A3OPRL1OPRM1ALDH1A1LMNA | |
| SCHEMBL11070722 | 0.81 | OPRL1 (0.40) | OPRL1OPRM1KMT2ACCR1 | |
| SCHEMBL11075806 | 0.81 | SLC6A3 (0.33) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |