Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.35 |
| ▸ | CCR1 | P32246 | 6/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075720 | 0.94 | SLC6A3 (0.35) | SLC6A3OPRL1CCR1OPRM1OPRK1 | |
| SCHEMBL11071160 | 0.93 | SLC6A3 (0.38) | SLC6A3OPRL1CCR1OPRM1OPRK1 | |
| SCHEMBL11078182 | 0.90 | SLC6A3 (0.32) | SLC6A3OPRL1 | |
| SCHEMBL11070722 | 0.87 | OPRL1 (0.40) | OPRL1CCR1OPRM1KMT2A | |
| SCHEMBL11075806 | 0.86 | SLC6A3 (0.33) | SLC6A3 | |
| SCHEMBL11078360 | 0.86 | OPRL1 (0.37) | SLC6A3OPRL1CCR1OPRM1OPRK1 | |
| SCHEMBL11074300 | 0.84 | SLC6A3 (0.32) | SLC6A3OPRL1OPRM1OPRK1 | |
| SCHEMBL11073972 | 0.81 | OPRL1 (0.40) | SLC6A3OPRL1CCR1OPRM1KMT2A | |
| SCHEMBL11069281 | 0.81 | OPRL1 (0.46) | OPRL1CCR1OPRM1OPRK1CCR2 | |
| SCHEMBL11067195 | 0.81 | SLC6A3 (0.34) | SLC6A3PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |