Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075950 | 0.84 | HTR1A (0.51) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11075808 | 0.78 | GRM5 (0.50) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11075306 | 0.77 | GRM5 (0.55) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11071509 | 0.77 | GRM5 (0.54) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11068370 | 0.76 | GRM5 (0.51) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11071559 | 0.76 | RAB9A (0.67) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL5178383 | 0.74 | GRM5 (0.54) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL11052726 | 0.74 | HRH3 (0.51) | HRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL11074430 | 0.73 | HRH3 (0.48) | HRH3GRM5GRM1SLC6A7SCD | |
| SCHEMBL5987878 | 0.72 | GRM5 (0.58) | HRH3GRM5GRM1SLC6A7SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476128-A | ANTIARTHRITIC AGENTS ANTIBODY INHIBITORS | MITSUITOATSU CHEMICALS, INC. (JP) | 1984-10-09 | — | — | US | disclosed |