SCHEMBL11075844

SCHEMBL11075844

O=C(F)C(F)(F)C(F)(F)C(F)(F)C(=O)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28389324 0.82 THRB (0.33) THRB
SCHEMBL942872 0.81 THRB (0.42) THRB
SCHEMBL4184561 0.81 THRB (0.36) THRB
SCHEMBL15758530 0.79 THRB (0.40) THRB
SCHEMBL3955796 0.79 THRB (0.52) THRB
SCHEMBL6559846 0.77 THRB (0.56) THRB
SCHEMBL221793 0.75 THRB (0.33) THRB
SCHEMBL426883 0.75 THRB (0.46) THRB
SCHEMBL6403975 0.75 THRB (0.33) THRB
SCHEMBL957780 0.74 THRB (0.43) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4469641-A INTERMEDIATES FOR PERFLUOROISOPROPYLKETOCARBOXYLIC ACID FLUORIDES HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-04 US disclosed
EP-0047947-B1 OMEGA-FLUOROSULPHATO-PERFLUORO-(2-METHYLALKANE-3-ONES) AND PROCESS FOR THE PRODUCTION OF PERFLUOROISOPROPYL-KETO-CARBOXYLIC-ACID FLUORIDES FROM THE FIRST MENTIONED COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1984-03-14 EP disclosed
EP-0047947-A1 Omega-fluorosulphato-perfluoro-(2-methylalkane-3-ones) and process for the production of perfluoroisopropyl-keto-carboxylic-acid fluorides from the first mentioned compounds HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-24 EP disclosed