SCHEMBL6403975

SCHEMBL6403975

O=C(C(F)(F)C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)F.O=C(C(F)(F)C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221793 1.00 THRB (0.33) THRB
SCHEMBL22121300 0.87
SCHEMBL19064226 0.83 LIPA (0.31)
SCHEMBL1813630 0.82 THRB (0.38) THRB
SCHEMBL982803 0.82 THRB (0.32) THRB
SCHEMBL942872 0.81 THRB (0.42) THRB
SCHEMBL15758530 0.79 THRB (0.40) THRB
SCHEMBL3955796 0.79 THRB (0.52) THRB
SCHEMBL9934913 0.79 ALDH1A1 (0.33)
SCHEMBL1360173 0.79 THRB (0.36) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050188697-A1 Fluorinated ketone and fluorinated ethers as working fluids for thermal energy conversion HONEYWELL CORPORATION 2005-09-01 US disclosed