Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076083 | 1.00 | MAPT (0.56) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL1510077 | 0.83 | HCAR2 (0.52) | MAPTLMNAPLIN1RECQLPLIN5 | |
| SCHEMBL1510079 | 0.83 | HCAR2 (0.52) | MAPTLMNAPLIN1RECQLPLIN5 | |
| SCHEMBL27700256 | 0.83 | CYP1A1 (0.62) | MAPTLMNACYP1B1CYP3A4KMT2A | |
| SCHEMBL8916912 | 0.78 | HDAC3 (0.32) | MAPTLMNAPLIN1RECQLPLIN5 | |
| SCHEMBL20448389 | 0.78 | CCNC (0.34) | MAPTLMNAPLIN1RECQLPLIN5 | |
| SCHEMBL20448409 | 0.74 | ALDH1A1 (0.41) | MAPTMAOBRAB9AKMT2AALDH1A1 | |
| SCHEMBL339221 | 0.73 | — | — | |
| SCHEMBL2954318 | 0.73 | MAPT (0.70) | MAPTMAOBLMNABCHECYP1B1 | |
| SCHEMBL5664436 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433152-A | ANTIINFLAMMATORY AGENT, ANTIALLERGEN OR ANTICOAGULANT | NIPPON CHEMIPHAR CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |