Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | USP7 | Q93009 | 2/20 | 0.47 |
| ▸ | USP8 | P40818 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | BCL2 | P10415 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266802 | 0.81 | USP8 (0.58) | MAOAMAOBUSP7USP8USP47 | |
| SCHEMBL7796247 | 0.78 | MAOA (0.62) | ESR2MAOAMAOBESR1UGT1A1 | |
| SCHEMBL31289519 | 0.78 | USP8 (0.58) | MAOAMAOBUSP7USP8MCL1 | |
| SCHEMBL939194 | 0.78 | USP8 (0.58) | MAOAMAOBUSP7USP8MCL1 | |
| Methane SCHEMBL27726276 | 0.76 | USP8 (0.56) | MAOAMAOBUSP7USP8MCL1 | |
| SCHEMBL8486849 | 0.75 | USP8 (0.48) | ESR2MAOAMAOBUSP7USP8 | |
| SCHEMBL31221958 | 0.75 | USP8 (0.51) | MAOAMAOBTTRUSP7USP8 | |
| SCHEMBL11137759 | 0.75 | APAF1 (0.48) | ESR2MAOAMAOBUSP7USP8 | |
| SCHEMBL26187370 | 0.74 | ELANE (0.59) | MAOAMAOBTTRUSP7USP8 | |
| SCHEMBL30610019 | 0.74 | ELANE (0.59) | MAOAMAOBTTRUSP7USP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447420-A | Fluorenone esters of phosphoric and phosphonic acids as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |