Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18426330 | 0.85 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTTSMN1; SMN2NPC1 | |
| SCHEMBL14496920 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL34850 | 0.81 | SMN1; SMN2 (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2NPC1 | |
| SCHEMBL11632958 | 0.80 | MAPT (0.55) | KDM4EHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL3919280 | 0.80 | SMN1; SMN2 (0.70) | ALDH1A1HTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL7373951 | 0.80 | LMNA (0.62) | KDM4EHTTSMN1; SMN2NPC1LMNA | |
| SCHEMBL11165713 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHTTSMN1; SMN2NPC1 | |
| SCHEMBL8189741 | 0.78 | MAPT (0.60) | ALDH1A1KDM4ESMN1; SMN2NPC1LMNA | |
| SCHEMBL7372081 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1KDM4EHTTSMN1; SMN2NPC1 | |
| SCHEMBL6267396 | 0.77 | LMNA (0.48) | ALDH1A1KDM4EHTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232467-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |
| EP-0102195-A2 | Substituted aza bicycloalkyl derivatives with dopamine antagonist activity | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |