Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8303787 | 1.00 | POLB (0.65) | POLBCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL8303785 | 1.00 | POLB (0.65) | POLBCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL2805466 | 0.82 | POLB (0.53) | POLBMAPTCYP1A2HPGDALOX12 | |
| SCHEMBL11066346 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11066332 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2805463 | 0.82 | POLB (0.53) | POLBMAPTCYP1A2HPGDALOX12 | |
| SCHEMBL11076121 | 0.82 | POLB (0.53) | POLBMAPTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1239325 | 0.81 | POLB (0.51) | POLBMAPTCYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL11083067 | 0.81 | POLB (0.51) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11083064 | 0.81 | POLB (0.51) | POLBHPGDSMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465630-A | Tetraazaannulene cobalt complex compounds and method for preparation therefor | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | disclosed |
| EP-0073456-A1 | Tetraazaannulene cobalt complex compounds and method for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-03-09 | — | — | EP | disclosed |