Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081308 | 0.94 | HSD17B10 (0.44) | ALDH1A1HSD17B10MAPTHPGDKMT2A | |
| SCHEMBL11078261 | 0.89 | CYP3A4 (0.38) | ALDH1A1HSD17B10MAPTHPGDKMT2A | |
| SCHEMBL11306239 | 0.85 | MAPK1 (0.46) | ALDH1A1MAPTKMT2ACYP3A4TDP1 | |
| SCHEMBL11306235 | 0.85 | MAPK1 (0.46) | ALDH1A1MAPTKMT2ACYP3A4TDP1 | |
| SCHEMBL10706061 | 0.85 | MAPK1 (0.46) | ALDH1A1MAPTKMT2ACYP3A4TDP1 | |
| SCHEMBL8743305 | 0.85 | PLCG1 (0.41) | ALDH1A1L3MBTL1PLCG1 | |
| SCHEMBL8743301 | 0.85 | PLCG1 (0.41) | ALDH1A1L3MBTL1PLCG1 | |
| SCHEMBL11080377 | 0.83 | CTDSP1 (0.39) | ALDH1A1CTDSP1L3MBTL1 | |
| SCHEMBL11753680 | 0.83 | CTDSP1 (0.39) | ALDH1A1CTDSP1L3MBTL1 | |
| SCHEMBL11077487 | 0.83 | CTSS (0.43) | ALDH1A1MAPTCYP3A4PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |