Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 7/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743301 | 1.00 | PLCG1 (0.41) | PLCG1NAAACTSBCTSSCTSK | |
| SCHEMBL11077487 | 0.92 | CTSS (0.43) | PLCG1CTSBCTSSCTSKALDH1A1 | |
| SCHEMBL10706061 | 0.89 | MAPK1 (0.46) | PLCG1ALDH1A1L3MBTL1 | |
| Biphenyl SCHEMBL10337735 | 0.89 | NAAA (0.44) | PLCG1NAAAELANE | |
| SCHEMBL11306235 | 0.89 | MAPK1 (0.46) | PLCG1ALDH1A1L3MBTL1 | |
| SCHEMBL11306239 | 0.89 | MAPK1 (0.46) | PLCG1ALDH1A1L3MBTL1 | |
| SCHEMBL11076122 | 0.85 | ALDH1A1 (0.38) | PLCG1ALDH1A1L3MBTL1 | |
| SCHEMBL11081835 | 0.83 | CTSS (0.46) | CTSBCTSSCTSKALDH1A1 | |
| SCHEMBL11753680 | 0.83 | CTDSP1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL11080377 | 0.83 | CTDSP1 (0.39) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387448-B1 | Photochemical conversion of cephalosporins, 1-carba(dethia)cephalosporins and 1-oxa(1-dethia)cephalosporins | LILLY CO ELI (US) | 1997-01-08 | — | — | EP | disclosed |
| US-4888100-A | ULTRAVIOLET RADIATION | ELI LILLY AND COMPANY (US) | 1989-12-19 | — | — | US | disclosed |