SCHEMBL11076227

SCHEMBL11076227

CCCCCCCCCC(C)=CC(CC)CCCC

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DNM1 Q05193 2/20 0.37
CES2 O00748 3/20 0.35
CES1 P23141 3/20 0.35
FFAR4 Q5NUL3 1/20 0.35
FFAR1 O14842 1/20 0.35
ALDH1A1 P00352 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
GPR84 Q9NQS5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11076224 1.00 TSHR (0.45) TSHRSMN1; SMN2DNM1CES2CES1
SCHEMBL31744466 0.87 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1
SCHEMBL31744479 0.85 CA2 (0.44) TSHRSMN1; SMN2ALDH1A1
SCHEMBL31744474 0.80 TSHR (0.41) TSHRSMN1; SMN2ALDH1A1
SCHEMBL11972934 0.78 TSHR (0.45) TSHRSMN1; SMN2DNM1FFAR1GPR84
SCHEMBL29253927 0.78 TSHR (0.45) TSHRSMN1; SMN2DNM1FFAR1GPR84
SCHEMBL6910847 0.77 TSHR (0.54) TSHRSMN1; SMN2DNM1ALDH1A1
SCHEMBL19480573 0.76 LMNA (0.38) TSHRCES2CES1ALDH1A1SLC22A6
SCHEMBL4584802 0.74 TSHR (0.39) TSHRCES2CES1FFAR4FFAR1
SCHEMBL26977240 0.72 LMNA (0.38) TSHRSMN1; SMN2CES2CES1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005947-B2 Modified hydrocarbon resins as fluid loss additives INGEVITY SOUTH CAROLINA, LLC (US) 2018-06-26 US disclosed
EP-3071782-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES Georgia-Pacific Chemicals LLC (US) 2016-09-28 EP disclosed
CN-105874153-A Modified hydrocarbon resins as fluid loss additives 佐治亚-太平洋化工品有限公司 2016-08-17 CN disclosed
WO-2015077215-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-05-28 WO disclosed
US-20150136402-A1 MODIFIED HYDROCARBON RESINS AS FLUID LOSS ADDITIVES GEORGIA-PACIFIC CHEMICALS LLC (US) 2015-05-21 US disclosed
US-4433100-A DICYCLOPENTADIENE, NON-AROMATIC UNSATURATED HYDROCARBON, FATTY OR ROSIN ACID NEVILLE CHEMICAL COMPANY (US) 1984-02-21 US disclosed