Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065324 | 0.83 | MAPT (0.46) | XDHKMT2AMEN1GAATP53 | |
| SCHEMBL11065025 | 0.83 | MAPT (0.43) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL3640007 | 0.79 | MEN1 (0.56) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL29825622 | 0.79 | MEN1 (0.56) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL27654631 | 0.79 | MAPT (0.58) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL11077235 | 0.78 | TP53 (0.46) | XDHKMT2AMEN1LMNATP53 | |
| SCHEMBL11233556 | 0.76 | MAPT (0.54) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL2701430 | 0.75 | MAPT (0.57) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL5095572 | 0.74 | MEN1 (0.51) | XDHKMT2AMEN1KCNH2GAA | |
| SCHEMBL10829024 | 0.74 | MAPT (0.56) | XDHKMT2AMEN1KCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | claimed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | claimed |
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | disclosed |