Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065025 | 0.86 | MAPT (0.43) | MAPTTP53GAAANO1NPC1 | |
| SCHEMBL28665700 | 0.83 | HSD17B10 (0.49) | MAPTSMN1; SMN2ALDH1A1TP53NPC1 | |
| SCHEMBL11076330 | 0.83 | XDH (0.49) | MAPTSMN1; SMN2TP53GAANPC1 | |
| SCHEMBL11077235 | 0.81 | TP53 (0.46) | MAPTALDH1A1TP53ANO1NPC1 | |
| SCHEMBL10829015 | 0.81 | MAOB (0.52) | MAPTSMN1; SMN2ALDH1A1TP53ANO1 | |
| SCHEMBL11077232 | 0.77 | CASP3 (0.44) | MAPTALDH1A1TP53GAAANO1 | |
| SCHEMBL11336670 | 0.77 | MEN1 (0.56) | MAPTSMN1; SMN2ALDH1A1TP53GAA | |
| SCHEMBL5095572 | 0.74 | MEN1 (0.51) | MAPTSMN1; SMN2ALDH1A1TP53GAA | |
| SCHEMBL10829024 | 0.74 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1TP53GAA | |
| Eclazolast SCHEMBL636302 | 0.74 | MEN1 (0.46) | MAPTALDH1A1TP53ANO1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | claimed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | claimed |
| US-4490373-A | BENZOXAZOLE-2-CARBOXYLIC ACID AMIDES | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0127066-A2 | Composition for treating asthma | USV PHARMACEUTICAL CORPORATION (US) | 1984-12-05 | — | — | EP | disclosed |