Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076388 | 1.00 | CTDSP1 (0.36) | CTDSP1L3MBTL1ALDH1A1TSHRMAPK10 | |
| SCHEMBL11079432 | 0.86 | CTDSP1 (0.44) | CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11079426 | 0.86 | CTDSP1 (0.44) | CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11383109 | 0.85 | CTDSP1 (0.38) | CTDSP1L3MBTL1ALDH1A1TSHRMAPK10 | |
| SCHEMBL11077532 | 0.83 | CTDSP1 (0.37) | CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11077529 | 0.83 | CTDSP1 (0.37) | CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11075259 | 0.83 | L3MBTL1 (0.39) | CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11077991 | 0.82 | PTGS1 (0.37) | — | |
| SCHEMBL11077988 | 0.82 | PTGS1 (0.37) | — | |
| SCHEMBL11082041 | 0.81 | PTGS1 (0.36) | CTDSP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |