Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | ENO1 | P06733 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082044 | 1.00 | PTGS1 (0.36) | PTGS1USP2CYP3A4CHRM1PLCG1 | |
| SCHEMBL11077988 | 0.91 | PTGS1 (0.37) | PTGS1USP2CYP3A4CHRM1 | |
| SCHEMBL11077991 | 0.91 | PTGS1 (0.37) | PTGS1USP2CYP3A4CHRM1 | |
| SCHEMBL11080712 | 0.90 | CTSS (0.38) | PTGS1USP2CYP3A4CHRM1ALDH1A1 | |
| SCHEMBL11112544 | 0.88 | PTGS1 (0.38) | PTGS1CYP3A4PLCG1ELANEALDH1A1 | |
| SCHEMBL11086460 | 0.84 | CTSL (0.33) | PTGS1USP2CYP3A4CHRM1ALDH1A1 | |
| SCHEMBL11078750 | 0.84 | PLCG1 (0.39) | PTGS1USP2CYP3A4CHRM1PLCG1 | |
| SCHEMBL11096167 | 0.82 | CYP3A4 (0.31) | PTGS1USP2CYP3A4CHRM1ALDH1A1 | |
| SCHEMBL11076388 | 0.81 | CTDSP1 (0.36) | ALDH1A1L3MBTL1CTDSP1 | |
| SCHEMBL11076385 | 0.81 | CTDSP1 (0.36) | ALDH1A1L3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |