Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080871 | 0.87 | MEN1 (0.63) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL14646372 | 0.86 | MEN1 (0.72) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL11075285 | 0.83 | MEN1 (0.67) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL29732712 | 0.80 | MEN1 (0.70) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL4196255 | 0.80 | MEN1 (0.70) | MEN1KMT2APOLBFABP4MGAM | |
| Trifenagrel SCHEMBL31058836 | 0.80 | MEN1 (0.63) | MEN1KMT2APOLBFABP4MGAM | |
| Trifenagrel SCHEMBL4428157 | 0.80 | MEN1 (0.63) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL11070400 | 0.79 | MEN1 (0.54) | MEN1KMT2APOLBFABP4MGAM | |
| Trifenagrel SCHEMBL11078277 | 0.79 | MEN1 (0.62) | MEN1KMT2APOLBFABP4MGAM | |
| SCHEMBL11074884 | 0.79 | MEN1 (0.53) | MEN1KMT2APOLBFABP4MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | disclosed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | disclosed |