Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646372 | 0.91 | MEN1 (0.72) | MEN1KMT2APOLBTP53MGAM | |
| SCHEMBL29732712 | 0.84 | MEN1 (0.70) | MEN1KMT2APOLBTP53MGAM | |
| SCHEMBL4196255 | 0.84 | MEN1 (0.70) | MEN1KMT2APOLBTP53MGAM | |
| SCHEMBL11080871 | 0.84 | MEN1 (0.63) | MEN1KMT2APOLBTP53MGAM | |
| Trifenagrel SCHEMBL31058836 | 0.84 | MEN1 (0.63) | MEN1KMT2APOLBTP53MGAM | |
| Trifenagrel SCHEMBL4428157 | 0.84 | MEN1 (0.63) | MEN1KMT2APOLBTP53MGAM | |
| Trifenagrel SCHEMBL11078277 | 0.83 | MEN1 (0.62) | MEN1KMT2APOLBMGAMKDM4E | |
| SCHEMBL11076584 | 0.83 | MEN1 (0.62) | MEN1KMT2APOLBTP53MGAM | |
| SCHEMBL11080279 | 0.82 | MEN1 (0.61) | MEN1KMT2APOLBTP53MGAM | |
| SCHEMBL11072103 | 0.81 | MEN1 (0.60) | MEN1KMT2APOLBTP53MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0058890-A1 | Antithrombotic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-01 | — | — | EP | claimed |
| EP-0058890-B1 | ANTITHROMBOTIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-09-26 | — | — | EP | disclosed |