SCHEMBL4196255

SCHEMBL4196255

CCOc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)[nH]1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
POLB P06746 2/20 0.70
MAPT P10636 3/20 0.68
MGAM O43451 1/20 0.57
PDE5A O76074 1/20 0.56
GUSB P08236 1/20 0.55
KDM4E B2RXH2 1/20 0.53
SMPD3 Q9NY59 2/20 0.51
FABP4 P15090 1/20 0.51
NOX1 Q9Y5S8 3/20 0.50
TP53 P04637 2/20 0.50
MAPK13 O15264 2/20 0.49
MAPK12 P53778 2/20 0.49
MAPK11 Q15759 2/20 0.49
MAPK14 Q16539 2/20 0.49
RAF1 P04049 1/20 0.49
MAPK9 P45984 1/20 0.49
THRB P10828 1/20 0.48
NT5E P21589 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732712 1.00 MEN1 (0.70) MEN1KMT2APOLBMAPTMGAM
SCHEMBL31429639 0.89 MAPT (0.61) MEN1KMT2APOLBMAPTMGAM
SCHEMBL14646372 0.87 MEN1 (0.72) MEN1KMT2APOLBMAPTMGAM
SCHEMBL29361514 0.84 MEN1 (0.65) MEN1KMT2APOLBMAPTMGAM
SCHEMBL83914 0.84 MEN1 (0.65) MEN1KMT2APOLBMAPTMGAM
SCHEMBL11080279 0.84 MEN1 (0.61) MEN1KMT2APOLBMAPTMGAM
SCHEMBL11075285 0.84 MEN1 (0.67) MEN1KMT2APOLBMAPTMGAM
Trifenagrel SCHEMBL31058836 0.83 MEN1 (0.63) MEN1KMT2APOLBMAPTMGAM
SCHEMBL22639164 0.83 KMT2A (0.74) MEN1KMT2APOLBMAPTMGAM
Trifenagrel SCHEMBL4428157 0.83 MEN1 (0.63) MEN1KMT2APOLBMAPTMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180325112-A1 INSECTICIDAL COMPOSITIONS AND METHODS MONSANTO TECHNOLOGY LLC 2018-11-15 US claimed
EP-3377486-A1 INSECTICIDAL COMPOSITIONS AND METHODS Monsanto Technology LLC (US) 2018-09-26 EP claimed
EP-3377486-B1 METHOD OF CONTROLLING INSECT PESTS MONSANTO TECHNOLOGY LLC (US) 2024-09-18 EP disclosed
US-11771088-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2023-10-03 US disclosed
US-11771088-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2023-10-03 US disclosed
US-11771088-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2023-10-03 US disclosed
CN-108349953-B Pesticidal compositions and methods 孟山都技术公司 2022-06-17 CN disclosed
US-20210030001-A1 INSECTICIDAL COMPOSITIONS AND METHODS MONSANTO TECHNOLOGY LLC (US) 2021-02-04 US disclosed
US-20210030001-A1 INSECTICIDAL COMPOSITIONS AND METHODS MONSANTO TECHNOLOGY LLC (US) 2021-02-04 US disclosed
US-10827755-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2020-11-10 US disclosed
US-10827755-B2 Insecticidal compositions and methods MONSANTO TECHNOLOGY LLC (US) 2020-11-10 US disclosed
US-20180325112-A1 INSECTICIDAL COMPOSITIONS AND METHODS MONSANTO TECHNOLOGY LLC 2018-11-15 US disclosed
CN-108602238-A Pattern forming method, production method of processed substrate, production method of optical component, production method of circuit substrate, production method of electronic component, and production method of imprint mold 佳能株式会社 2018-09-28 CN disclosed
EP-3377486-A1 INSECTICIDAL COMPOSITIONS AND METHODS Monsanto Technology LLC (US) 2018-09-26 EP disclosed
CN-108490737-A A kind of photosensitive polymer combination and application thereof 浙江福斯特新材料研究院有限公司 2018-09-04 CN disclosed
EP-1264212-B1 ELEMENTS FOR FORMING PRINT-OUT IMAGES DU PONT (US) 2009-02-18 EP disclosed
US-6869755-B2 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY (US) 2005-03-22 US disclosed
EP-1264212-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. du Pont de Nemours and Company (US) 2002-12-11 EP disclosed
US-20020146649-A1 Elements for forming print-out images E. I. DU PONT DE NEMOURS AND COMPANY 2002-10-10 US disclosed
WO-2001067175-A2 ELEMENTS FOR FORMING PRINT-OUT IMAGES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210030001-A1 INSECTICIDAL COMPOSITIONS AND METHODS INMT, CYCS, TH MEN1 3368/4885KMT2A 1498/4885POLB 4790/4885
US-11771088-B2 Insecticidal compositions and methods INMT, CYCS, TH MEN1 3368/4885KMT2A 1498/4885POLB 4790/4885
US-20180325112-A1 INSECTICIDAL COMPOSITIONS AND METHODS INMT, CYCS, TH MEN1 3368/4885KMT2A 1498/4885POLB 4790/4885
US-10827755-B2 Insecticidal compositions and methods INMT, CYCS, TH MEN1 3368/4885KMT2A 1498/4885POLB 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.