Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249451 | 1.00 | SLC6A4 (0.42) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11230125 | 1.00 | SLC6A4 (0.42) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL8396857 | 0.85 | SMN1; SMN2 (0.38) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11081130 | 0.80 | SLC6A4 (0.55) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11077730 | 0.80 | SLC6A4 (0.55) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11076649 | 0.78 | SIGMAR1 (0.49) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11076652 | 0.78 | SIGMAR1 (0.49) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11079211 | 0.78 | SIGMAR1 (0.49) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11550690 | 0.77 | SLC6A4 (0.56) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT | |
| SCHEMBL11550220 | 0.77 | SLC6A4 (0.56) | SLC6A4SIGMAR1SLC6A2SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435572-A | FROM 3-METHOXYBENZALDEHYDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-03-06 | — | — | US | disclosed |
| US-4346224-A | MORPHINE ANALOGS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1982-08-24 | — | — | US | disclosed |
| US-4289882-A | MORPHINE ANALOG ANALGESICS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 1981-09-15 | — | — | US | disclosed |
| US-4189583-A | FROM 1-METHYL-2-OXO-3-METHYLENE-4-(3'-METHOXYPHENYL)-4 -(CARBOXYMETHYLENE)PIPERIDINE BY CYCLIZATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-02-19 | — | — | US | disclosed |