Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075824 | 0.92 | OPRL1 (0.47) | OPRL1KDM4EOPRM1MEN1GAA | |
| SCHEMBL11073228 | 0.91 | OPRL1 (0.46) | OPRL1KDM4EOPRM1MEN1GAA | |
| SCHEMBL11073243 | 0.87 | OPRL1 (0.51) | OPRL1KDM4EOPRM1MAPK1TACR1 | |
| SCHEMBL11075826 | 0.86 | OPRL1 (0.50) | OPRL1KDM4EOPRM1MAPTMAPK1 | |
| SCHEMBL11066160 | 0.84 | OPRL1 (0.54) | OPRL1OPRM1TACR1 | |
| SCHEMBL11073728 | 0.83 | OPRL1 (0.52) | OPRL1OPRM1MEN1KMT2ATACR1 | |
| SCHEMBL11075750 | 0.79 | OPRM1 (0.46) | OPRL1OPRM1KMT2AACHELMNA | |
| Hydrochloric Acid SCHEMBL11099770 | 0.78 | OPRM1 (0.45) | OPRL1OPRM1KMT2AACHELMNA | |
| SCHEMBL11097716 | 0.76 | OPRM1 (0.43) | OPRL1OPRM1ACHELMNAALDH1A1 | |
| SCHEMBL11076093 | 0.75 | OPRL1 (0.50) | OPRL1OPRM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |