Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075826 | 0.97 | OPRL1 (0.50) | OPRL1GRIN1GRIN2AGRIN2BALDH1A1 | |
| SCHEMBL11073728 | 0.90 | OPRL1 (0.52) | OPRL1GRIN1GRIN2BALDH1A1HTT | |
| SCHEMBL11076744 | 0.87 | OPRL1 (0.47) | OPRL1ALDH1A1KDM4EHTTMAPK1 | |
| SCHEMBL11075824 | 0.86 | OPRL1 (0.47) | OPRL1ALDH1A1KDM4EMAPK1OPRM1 | |
| SCHEMBL11073228 | 0.86 | OPRL1 (0.46) | OPRL1ALDH1A1KDM4EHTTMAPK1 | |
| SCHEMBL11066160 | 0.85 | OPRL1 (0.54) | OPRL1OPRM1SLC6A4TACR1 | |
| SCHEMBL11069247 | 0.77 | OPRL1 (0.69) | OPRL1ALDH1A1MAPK1OPRM1CHRM2 | |
| SCHEMBL11095875 | 0.76 | OPRM1 (0.49) | OPRL1GRIN1GRIN2AGRIN2BOPRM1 | |
| SCHEMBL11076093 | 0.76 | OPRL1 (0.50) | OPRL1OPRM1SLC6A4 | |
| SCHEMBL11076056 | 0.74 | OPRD1 (0.45) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |