SCHEMBL11076748

SCHEMBL11076748

Cc1cc(OC(C(=O)Nc2ccccc2)C(C)C)c(Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 2/20 0.47
ALDH1A1 P00352 5/20 0.43
LMNA P02545 5/20 0.43
RORC P51449 2/20 0.43
PKM P14618 1/20 0.43
MAPT P10636 3/20 0.43
HTR1E P28566 2/20 0.43
S1PR3 Q99500 2/20 0.43
GAA P10253 2/20 0.43
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
KMT2A Q03164 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.43
GPR27 Q9NS67 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11079552 0.88 KDM4E (0.55) ALDH1A1LMNAPKMMAPTGAA
SCHEMBL11072526 0.84 KLK7 (0.46) KLK7ALDH1A1LMNARORCPKM
SCHEMBL11082980 0.82 KLK7 (0.50) KLK7ALDH1A1LMNAMAPTGAA
SCHEMBL11081258 0.81 KDM4E (0.52) ALDH1A1LMNAPKMMAPTGAA
SCHEMBL11076398 0.80 KLK7 (0.47) KLK7ALDH1A1LMNARORCPKM
SCHEMBL11070398 0.78 HDAC3 (0.44) ALDH1A1LMNARORCMAPTGAA
SCHEMBL11074180 0.78 MAOB (0.46) ALDH1A1RORCPKMMAPTHTT
SCHEMBL11081530 0.78 KDM4E (0.52) ALDH1A1LMNAPKMMAPTGAA
SCHEMBL11072073 0.78 PKM (0.64) ALDH1A1LMNAPKMMAPTGAA
SCHEMBL11083153 0.78 ALDH1A1 (0.55) ALDH1A1LMNAPKMMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465507-A Herbicidal acetanilides MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1984-08-14 US disclosed