Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078319 | 0.85 | OPRL1 (0.41) | OPRL1HTR2AHRH1HTR2BGRIN2B | |
| SCHEMBL11070178 | 0.83 | OPRL1 (0.51) | OPRL1HTR2AGRIN2BKCNH2 | |
| SCHEMBL11066576 | 0.79 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL11071372 | 0.76 | OPRL1 (0.39) | OPRL1HTR2AHTR2BCCR3 | |
| SCHEMBL11073882 | 0.75 | OPRL1 (0.52) | OPRL1CCR3 | |
| SCHEMBL11081934 | 0.74 | OPRL1 (0.51) | OPRL1 | |
| SCHEMBL11069516 | 0.73 | OPRL1 (0.50) | OPRL1 | |
| SCHEMBL11074571 | 0.73 | OPRL1 (0.46) | OPRL1CCR3BCHE | |
| SCHEMBL11070148 | 0.72 | OPRL1 (0.49) | OPRL1 | |
| SCHEMBL11077902 | 0.72 | SLC6A4 (0.39) | OPRL1HTR2AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |