Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069648 | 0.82 | GRIN2B (0.47) | OPRL1HTR2AHTR2BOPRM1DRD2 | |
| SCHEMBL11071470 | 0.76 | SKP2 (0.40) | SLC6A4SLC6A3OPRL1OPRM1DRD2 | |
| SCHEMBL11076941 | 0.76 | HTR1D (0.40) | SLC6A4HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL11075816 | 0.75 | HTR2A (0.31) | OPRL1HTR2AHTR2CHRH1HTR2B | |
| SCHEMBL11076992 | 0.72 | OPRL1 (0.48) | OPRL1HTR2AHRH1HTR2B | |
| Ethylbenzene SCHEMBL11069651 | 0.72 | OPRL1 (0.47) | SLC6A4OPRL1OPRM1OPRK1 | |
| SCHEMBL11071584 | 0.72 | MEN1 (0.39) | SLC6A4SLC6A3HTR2AHTR2CHTR2B | |
| SCHEMBL11077899 | 0.72 | OPRL1 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11071936 | 0.71 | SLC6A4 (0.39) | SLC6A4SLC6A3OPRL1HTR2AHTR2C | |
| SCHEMBL11078784 | 0.71 | SLC6A4 (0.46) | SLC6A4SLC6A3OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |