Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084815 | 0.83 | HPGD (0.38) | BRD4SRD5A1 | |
| SCHEMBL11087338 | 0.82 | DRD2 (0.44) | BRD4 | |
| SCHEMBL11100035 | 0.81 | ATM (0.41) | — | |
| SCHEMBL11078137 | 0.81 | SLC6A2 (0.41) | — | |
| SCHEMBL11079789 | 0.81 | BRD4 (0.36) | BRD4SRD5A1 | |
| SCHEMBL11072826 | 0.79 | BRD4 (0.53) | BRD4SRD5A1 | |
| SCHEMBL11068920 | 0.77 | DRD2 (0.48) | — | |
| SCHEMBL11287944 | 0.75 | MGLL (0.35) | MGLLDPP4F2RNOTUM | |
| SCHEMBL24809401 | 0.75 | DRD2 (0.40) | MGLLDPP4F2RNOTUM | |
| SCHEMBL11079226 | 0.74 | MGLL (0.35) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024776-B1 | 4-PHENYL AND 5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES, AND PROCESS FOR PREPARING SAID DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0024776-A1 | 4-Phenyl and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, pharmaceutical compositions containing said derivatives, and process for preparing said derivatives | SYNTEX (U.S.A.) INC. (US) | 1981-03-11 | — | — | EP | disclosed |