Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31496743 | 0.98 | HTT (0.54) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL2378330 | 0.86 | L3MBTL1 (0.55) | HTTHPGDPOLBKDM4EKMT2A | |
| SCHEMBL2455545 | 0.85 | HPGD (0.54) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL2377252 | 0.84 | ALDH1A1 (0.55) | HTTHPGDGAAKDM4ESMN1; SMN2 | |
| SCHEMBL29816719 | 0.83 | HTT (0.65) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL31547828 | 0.83 | HTT (0.58) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL2302867 | 0.83 | HTT (0.58) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL12260970 | 0.82 | POLB (0.56) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL12260976 | 0.82 | POLB (0.56) | HTTHPGDPOLBGAAKDM4E | |
| SCHEMBL2380021 | 0.82 | FNTA (0.52) | HTTKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098951-A2 | Aminobenzamide derivatives and preparation thereof | STERLING DRUG INC. (US) | 1984-01-25 | — | — | EP | disclosed |