Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRND | Q07001 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11070705 | 0.85 | SLC6A4 (0.44) | SLC6A2SLC6A4SLC6A3RAB9AOPRL1 | |
| Morpholine SCHEMBL11078533 | 0.79 | OPRL1 (0.55) | OPRL1 | |
| Morpholine SCHEMBL11074378 | 0.77 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| Morpholine SCHEMBL11077268 | 0.77 | OPRM1 (0.39) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL11071130 | 0.74 | OPRM1 (0.54) | SLC6A2SLC6A4SLC6A3OPRL1ADRB1 | |
| Morpholine SCHEMBL11069855 | 0.73 | DRD2 (0.39) | SLC6A2SLC6A4SLC6A3RAB9ACHRNA1 | |
| Morpholine SCHEMBL11075735 | 0.72 | SLC6A4 (0.40) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| Morpholine SCHEMBL11071701 | 0.71 | OPRL1 (0.38) | MEN1KMT2AKDM4EOPRL1 | |
| Morpholine SCHEMBL11073855 | 0.70 | OPRM1 (0.41) | SLC6A2SLC6A4SLC6A3OPRL1 | |
| SCHEMBL22112324 | 0.68 | SLC6A4 (0.62) | SLC6A2SLC6A4SLC6A3OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |