Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078183 | 0.86 | BRD4 (0.35) | BACE1 | |
| SCHEMBL11085800 | 0.78 | SRD5A1 (0.36) | BACE1 | |
| SCHEMBL11077942 | 0.75 | DRD3 (0.39) | ATM | |
| SCHEMBL11101543 | 0.75 | BACE1 (0.33) | BACE1ATM | |
| SCHEMBL11281643 | 0.74 | — | — | |
| SCHEMBL11079502 | 0.73 | GABRP (0.33) | — | |
| SCHEMBL11078142 | 0.73 | BRD4 (0.33) | — | |
| SCHEMBL11072826 | 0.71 | BRD4 (0.53) | — | |
| SCHEMBL11087497 | 0.70 | BRD4 (0.38) | — | |
| SCHEMBL11090881 | 0.69 | SRD5A1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024776-B1 | 4-PHENYL AND 5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES, AND PROCESS FOR PREPARING SAID DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1984-12-27 | — | — | EP | disclosed |
| EP-0024776-A1 | 4-Phenyl and 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, pharmaceutical compositions containing said derivatives, and process for preparing said derivatives | SYNTEX (U.S.A.) INC. (US) | 1981-03-11 | — | — | EP | disclosed |