Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701806 | 0.78 | GPR119 (0.54) | ALDH1A1LMNAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL15134823 | 0.77 | ALDH1A1 (0.71) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL24597769 | 0.76 | ALDH1A1 (0.71) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL10244960 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL23903336 | 0.75 | ALDH1A1 (0.69) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL19231640 | 0.73 | ALDH1A1 (0.67) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL10282306 | 0.73 | ALDH1A1 (0.74) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL652785 | 0.73 | ALDH1A1 (0.66) | ALDH1A1LMNAKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL10968173 | 0.73 | TRPV1 (0.67) | ALDH1A1LMNAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11082813 | 0.73 | GFER (0.57) | ALDH1A1KDM4ESMN1; SMN2HSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |