SCHEMBL11077591

SCHEMBL11077591

CC1(C)CC(NCCNCO)CC(C)(C)N1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
POLB P06746 1/20 0.37
SLC2A1 P11166 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
EZH2 Q15910 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTT P42858 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10637656 0.88 GAA (0.46) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL9023360 0.88 GAA (0.46) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL10881805 0.87 GAA (0.41) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL8434608 0.86 GAA (0.50) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL4541846 0.83 GAA (0.42) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL7910369 0.82 GAA (0.45) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL11016741 0.81 GAA (0.41) GAAKDM4ELMNARECQLALDH1A1
Ammonia Solution, Strong SCHEMBL16678851 0.81 GAA (0.44) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL10637973 0.80 LMNA (0.41) GAAKDM4ELMNARECQLALDH1A1
SCHEMBL8790504 0.80 LMNA (0.41) GAAKDM4ELMNARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439565-A Oligomeric esteramides containing pendant hindered amine groups CIBA-GEIGY CORPORATION (US) 1984-03-27 US disclosed