SCHEMBL10637656

SCHEMBL10637656

CC1(C)CC(NCCNCCNCCNC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
ALDH1A1 P00352 4/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RECQL P46063 1/20 0.41
SLC2A1 P11166 1/20 0.40
POLB P06746 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36
RAD52 P43351 1/20 0.36
GFER P55789 1/20 0.36
KDM1A O60341 1/20 0.35
EZH2 Q15910 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9023360 1.00 GAA (0.46) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8434608 0.93 GAA (0.50) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11016741 0.92 GAA (0.41) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8790504 0.91 LMNA (0.41) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL10881805 0.91 GAA (0.41) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL10637973 0.91 LMNA (0.41) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL8789690 0.90 SLC2A1 (0.43) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL4541846 0.90 GAA (0.42) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL10640087 0.89 GAA (0.41) GAAKDM4ELMNAALDH1A1NPSR1
SCHEMBL11077591 0.88 GAA (0.41) GAAKDM4ELMNAALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7384504-B2 Light-stable and process-stable lignocellulosic materials and their production FPINNOVATIONS (CA) 2008-06-10 US disclosed
US-7384504-B2 Light-stable and process-stable lignocellulosic materials and their production FPINNOVATIONS (CA) 2008-06-10 US disclosed
EP-0061785-B2 Use of polyalkylpiperidine polyamines as curing agent for epoxy resins CIBA-GEIGY AG (CH) 1988-03-16 EP disclosed
US-4528374-A Polyalkylpiperidines CIBA-GEIGY CORPORATION (US) 1985-07-09 US disclosed
US-4525503-A POLYETHYLENE, POLYPROPYLENE CIBA-GEIGY S.P.A. (IT) 1985-06-25 US disclosed
US-4501837-A LIGHT, HEAT, AND OXIDATION STABILIZERS CIBA-GEIGY S.P.A. (IT) 1985-02-26 US disclosed
EP-0061785-B1 Use of polyalkylpiperidine polyamines as curing agent for epoxy resins CIBA-GEIGY AG (CH) 1985-02-20 EP disclosed
EP-0013665-B1 POLYMERIC POLYAMINO 1,3,5-TRIAZINES CONTAINING AT LEAST ONE POLYALKYLPIPERIDINE GROUP, THEIR PREPARATION, THEIR USE IN STABILIZING AN ORGANIC MATERIAL AND THE MATERIAL STABILIZED THEREWITH CIBA-GEIGY AG (CH) 1983-06-29 EP disclosed
US-4369321-A Piperidine derivatives which are stabilizers for synthetic polymers CHIMOSA CHIMICA ORGANICA S.P.A. (IT) 1983-01-18 US disclosed
EP-0061785-A1 Use of polyalkylpiperidine polyamines as curing agent for epoxy resins CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
US-4315859-A STABILIZES PROVIDE PHOTSTABILITY OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
EP-0013665-A1 Polymeric polyamino 1,3,5-triazines containing at least one polyalkylpiperidine group, their preparation, their use in stabilizing an organic material and the material stabilized therewith CIBA-GEIGY AG (CH) 1980-07-23 EP disclosed