Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.54 |
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | GSK3A | P49840 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL28313837 | 0.94 | MGLL (0.65) | MGLLFAAHPTGS1PTGS2GSK3A | |
| Styrene SCHEMBL28041677 | 0.92 | GSK3A (0.47) | MGLLFAAHPTGS1PTGS2GSK3A | |
| Styrene SCHEMBL11069701 | 0.92 | MGLL (0.46) | MGLLFAAHPTGS1PTGS2GSK3A | |
| Propene SCHEMBL7619747 | 0.81 | MGLL (0.68) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL59456 | 0.79 | MGLL (0.83) | MGLLFAAHPTGS1PTGS2GSK3A | |
| Styrene SCHEMBL4456585 | 0.78 | ALDH1A1 (0.56) | MGLLGSK3AGSK3BALDH1A1RAB9A | |
| Styrene SCHEMBL11801013 | 0.77 | ALDH1A1 (0.67) | ALDH1A1LMNATP53TSHRCES1 | |
| Styrene SCHEMBL10715462 | 0.77 | ALDH1A1 (0.67) | PTGS2ALDH1A1LMNATP53TSHR | |
| Styrene SCHEMBL1194200 | 0.77 | ALDH1A1 (0.67) | ALDH1A1LMNATP53TSHRCES1 | |
| Styrene SCHEMBL28104944 | 0.76 | MGLL (0.72) | MGLLFAAHPTGS1PTGS2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472553-A | WITH A RUBBER-MODIFIED COPOLYMER OF STYRENE AND MALEIMIDE | ETHYL CORPORATION (US) | 1984-09-18 | — | — | US | disclosed |
| US-4458046-A | BLEND TO IMPROVE HEAT DEFORMATION CHARACTERISTCS | ETHYL CORPORATION (US) | 1984-07-03 | — | — | US | disclosed |
| US-4388446-A | ELEVATED HEAT DEFLECTION TEMPERATURES | ETHYL CORPORATION (US) | 1983-06-14 | — | — | US | disclosed |