Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807183 | 0.87 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL6019991 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL11502178 | 0.85 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL9358466 | 0.81 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL11074576 | 0.79 | RAB9A (0.42) | ALDH1A1SMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL9358467 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL10397270 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL27437607 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL1416429 | 0.77 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 | |
| SCHEMBL11014423 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040179-B1 | PHENYLBENZOYL UREA | CIBA-GEIGY AG (CH) | 1984-08-29 | — | — | EP | disclosed |
| US-4418066-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0040179-A2 | Phenylbenzoyl urea | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |