Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077927 | 1.00 | LMNA (0.34) | LMNAHTTNPSR1POLQGPBAR1 | |
| SCHEMBL11072600 | 0.89 | GPBAR1 (0.38) | LMNAHTTNPSR1GPBAR1KMT2A | |
| SCHEMBL11072598 | 0.89 | GPBAR1 (0.38) | LMNAHTTNPSR1GPBAR1KMT2A | |
| SCHEMBL11079534 | 0.88 | POLQ (0.36) | LMNAHTTPOLQGPBAR1KMT2A | |
| SCHEMBL11079529 | 0.88 | POLQ (0.36) | LMNAHTTPOLQGPBAR1KMT2A | |
| SCHEMBL11073524 | 0.82 | TLR7 (0.39) | LMNAHTTNPSR1GPBAR1KMT2A | |
| SCHEMBL11073526 | 0.82 | TLR7 (0.39) | LMNAHTTNPSR1GPBAR1KMT2A | |
| SCHEMBL11073502 | 0.82 | TLR7 (0.39) | LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11073503 | 0.82 | TLR7 (0.39) | LMNAHTTNPSR1GPBAR1 | |
| SCHEMBL11077930 | 0.79 | PPARD (0.36) | LMNAHTTKMT2AGAAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431667-A | Imino ethers useful for controlling insect and arachnoid pests | THE UPJOHN COMPANY (US) | 1984-02-14 | — | — | US | disclosed |