Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077691 | 0.92 | ALDH1A1 (0.44) | SMN1; SMN2TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL3822964 | 0.89 | SMN1; SMN2 (0.61) | SMN1; SMN2TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL84288 | 0.86 | ALDH1A1 (0.47) | TDP1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL30237601 | 0.86 | ALDH1A1 (0.47) | TDP1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL14819082 | 0.86 | ALDH1A1 (0.41) | SMN1; SMN2TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL22315112 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL19927865 | 0.84 | ALDH1A1 (0.44) | SMN1; SMN2TDP1ALDH1A1LMNAKMT2A | |
| SCHEMBL13899502 | 0.82 | LPAR1 (0.52) | TDP1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL13923539 | 0.81 | APP (0.55) | TDP1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL13950254 | 0.81 | MAOA (0.40) | TDP1ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455431-A | Method for making bis-etherphthalimides | GENERAL ELECTRIC COMPANY (US) | 1984-06-19 | — | — | US | claimed |
| US-4455431-A | Method for making bis-etherphthalimides | GENERAL ELECTRIC COMPANY (US) | 1984-06-19 | — | — | US | disclosed |